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  ...medicine for depression or anxiety; Nancy Campbell RVT said... You'll need to ask your vet. There are so many alternatives for pain control that I think it is best left up to your vet to decide what would be best for your pet. Sorry, I couldn't be of more help. Laboratory Abnormalities: central nervous system (CNS) effects, which produce changes in mood, levels of awareness or perceptions and sensations. Most of these drugs also alter systems other than the CNS. But, not all centrally acting drugs are subject to abuse, which suggests that altering consciousness is not sufficient for a drug to have abuse potential. Among drugs that are abused, some appear to be more likely to lead to uncontrolled use than others, suggesting a possible hierarchy of drug-induced effects relative to abuse potential. Favorite it Lee CR, McTavish D, Sorkin EM. Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states. Drugs 1993;46:313-340. ...
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  ...Nausea My Viewing History | 9:31 PM, Anonymous said... This page has been so helpful...thanks to everyone whom shares their stories.I have a 12 year old boxer lab that suddenly couldn't lay down or walk very well. After I took him to the emergency vet, they put him on 2 pills of 50 mg of tramadol and predisone...which so far seems to have helped. He does however whince and pants at night. My vet said it was a side effect of Tramadol...but, I have seen a few entries where people have been told it is a sign of pain...Just was curious which is correct.Our vet still has not told us what is causing his pain possibly cancer on the spine or a ruptured disc...was curious what the different outcomes could be for either.Any help is appreciated.HS, Colorado ...
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  ...6:14 PM, Anonymous said... Well, it has been a few days. I'm pretty far off the subject of this discussion, but I'll stay with it since I started. To try and stay on subject, I'll start by saying we are still on Tramadol and have upped the dosage significantly. We were at 10mg total per day (5mg x 2 times) and we are up to 25 mg total (12.5mg x 2 times).We have taken some pretty big steps backwards. Our dog can barely walk. We have been back to the vet and had x-rays. The dog has three problem vertabra on the x-rays. Probably two of them are old injuries that healed, and one is the current problem. We aren't sure if it is a herniated/ruptured disc, or a spinal infection. Our vet (Upstate Veterinary Specialists - Dr. Dermot Jevens) seems to think the highest likelihood is the discospondylitis - or spinal infection. So we are agressively treating with Zeniquin (marbofloxacin) and hope to see results by Friday. (Today is Wed, and we started treatment on Tues)Making matters worse (and worrying me that it still could be a disc and we aren't treating that anymore) is that our dog started having severe vomiting and diarrhea and we believe that was brought on by the prednisone.So we have discontinued the prednisone for now and the diarrhea is almost completely gone and we aren't seeing any vomiting now but his mobility has greatly decreased at this point, and while he can still walk, he chooses not to if at all possible. We are hoping and praying that the anti-biotic starts making a difference soon.If that doesn't work, then we have to do a CT scan and try to find the exact disc that is the problem and see if we have surgical options. I'll be back in a few days to report.-TSGreenville, SC ...
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