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154 comments for withdrawls off of tramadolComment #137: tramadol dog pain management safe dosage ...Store tramadol at room temperature away from moisture and heat.
7:30 PM, Anonymous said... My dog was prescribed Tramdol after surgery they said as needed for pain for 3-5 days. She did not seem to be that bad off,but then I read on-line better to give it before pain is severe, so I just gave it. Then my friend over says she is in pain, but he is an ass, and I do not think she was and I gave it again anyhow. She whines so so so bad and falls to sleep immediately, I gave her two doses today and I will not give it to her again. She hates it like she looks at me like Mama you drugged me again. I can tell she hates it the speciality hospital she was at, which is said to be the best in NY(LIVS) probably gave too hish a dose (.10 ml q 8h prn. But they did not put shake well or refrigerate on bottle, they also do not communicate at all with you, and she was in to be spayed and they decided to operate on her bladder b/c they found a "pocket". I did not authorize this procedure nor would I have she was not having any symptoms. Icannot get an answer to what was wrong, one Dr. says cystitis, the other says a pocket, the other says a birth defect - a hole. I ask specifically to Dr. Inferno: "are there any side effects/problems/symptoms I can expect and he says NO, I call twice later that day , finally get a call back, ask him about her posturing every twenty seconds, and no urine coming out, and he says that is normal, to be expected. I asked, why when I specifically asked earlier you did not say this, he just repeated it is normal, but she was not doing it at their hospital. I asked if they took her out of her crate to evaluate her at all, b/c she would most likely not do this on herself in a crate. No, they had not. She went from a perfectly healthy dog to a poor uncomfortable distressed little thing, and they claim they did the right thing. I feel like calling up "Dr." Infernaro and telling him, "Rosie is doing backflips and whistling Dixie", and he would, pre programmed, indicate that this is normal. I feel violated, raped, like I had and have no control over the life and health of my dog, they took away her quality of life and no one gives a shit. She is just 5.5 months old. I am getting myself so worked up already. And I just have to sit here and take it, there is no justice but vigilante justice. My puppy is my child, my baby, and these animals destroyed her. Tell me how you do surgery without authorization? How?
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Incidence less than 5% possibly casually related: TABLE 2 lists adverse reactions that occurred with an incidence of less than 5% in clinical trials, and for which the possibility of a casual relationship with Ultram exists. Reactions are separated according to whether the incidence was greater than 1%. (TABLE 2)
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if you are pregnant, planning to become pregnant, or are breast-feeding if you are taking any prescription (especially depression medicines) or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you are allergic to codeine, a codeine-related medicine (eg, hydrocodone, dihydrocodeine, oxycodone), morphine, or a morphine-related medicine (eg, hydromorphone) if you have a history of alcohol abuse, substance abuse, or suicidal thoughts or behaviors if you have or recently have had any head injury, brain injury or tumor, increased pressure in the brain, or infection of the brain or nervous system if you have a history of stomach or intestinal problems, asthma or other lung or breathing problems, epilepsy, seizures, or chronic inflammation or ulceration of the bowels if you have had recent abdominal surgery if you have heart problems, liver problems (eg, hepatitis), kidney problems, thyroid problems, enlargement of the prostate gland, or urinary problems Some MEDICINES MAY INTERACT with Tramadol . Tell your health care provider if you are taking any other medicines, especially any of the following:
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Other adverse experiences, causal relationship unknown: A variety of other adverse events were reported infrequently in patients taking ULTRAM during clinical trials and/or reported in post-marketing experience. A causal relationship between ULTRAM and these events has not been determined. However, the most significant events are listed below as alerting information to the physician.
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This medicine will add to the effects of alcohol and other CNS depressants (medicine that causes drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Do not drink alcoholic beverages, and check with your medical doctor or dentist before taking any of the medicines listed above while you are using this medicine.
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12:03 PM, Anonymous said... My 5 year old lab/German Shepard mix died last night. I probably will never know why, but she was on Tramadol. She had a slipped disk at the base of her neck and Tramadol and Rimadryl were prescribed. That didn't work, so x-rays were taken and they then prescribed prednisone only. She was fine for a few days and then started walking funny. I called the vet and was told to put her back on the Tramadol. Within an hour, she started losing the use of her legs. She laid on her side (we kept rotating her) for two days and then she just passed. I guess I'll never know, but I somehow believe that the Tramadol didn't help her situation.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Click here for more information on
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During the preparation of the editorial there was a suggestion that the popularity of tramadol may be related to the availability of repeat prescriptions on the Pharmaceutical Benefits Scheme (PBS). The Editorial Executive Committee therefore invited the Pharmaceutical Benefits Advisory Committee (PBAC) to comment.
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9:35 AM, Anonymous said... My 11 year old (70#)greyhound came up with a limp after having a lean back chair hit her right front paw. She started to limp immediately and has not stopped. I took her to the vet,who seems to think it had nothing to do with the accident. He took x-rays and thinks she has osteosarcoma (bone cancer) I took her her to a cancer specialist who isn't sure of the cause either. She prescribed 50 mg of Tramadol every 12 hours and 1.5 mg of Medacam once a day. The limp is still not any better at all. I increased the Tramadol to 75 mg 2 x/day but she still limps the same. Can I increase either of these medications or are there other medications I can try. Thanks for all your wonderful advice on this blog.
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How to use Tramadol Oral Take this medication by mouth, either always with food or always without food, usually once daily or as directed by your doctor. If nausea occurs, consult your doctor or pharmacist about ways to decrease it (e.g., antihistamines, lying down for 1 to 2 hours with as little head movement as possible).Swallow this medication whole. Do not crush, chew, or split the tablet. Doing so would release the tramadol into your bloodstream all at once, possibly causing serious (sometimes fatal) side effects.The dosage is based on your medical condition and response to treatment. To reduce the risk of side effects, your doctor may tell you to gradually increase your dose when starting long-acting tramadol. The maximum recommended dose is 300 milligrams a day.If you have severe kidney disease (e.g., on dialysis) or severe liver disease (e.g., cirrhosis), regular-release tramadol is recommended instead of the long-acting form.Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.Follow your doctor's or pharmacist's instructions for the safe use of non-narcotic pain relievers (e.g., acetaminophen, ibuprofen). Ask your doctor or pharmacist for more details regarding your treatment.This medication may cause dependence, especially if it has been used regularly for an extended time or if it has been used in high doses. In such cases, withdrawal reactions (e.g., anxiety, sweating, sleeplessness, shaking, diarrhea, rapid breathing) may occur if you suddenly stop this drug. Also, if you are taking regular doses of narcotic medications for ongoing pain (e.g., cancer pain), starting tramadol may cause a withdrawal reaction. To prevent withdrawal reactions when stopping extended, regular treatment with this drug, gradually reduce the dosage as directed. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.Tell your doctor if your pain does not decrease or if it worsens.
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Veterinary Anesthesia Support Group (scroll through the alphabetical listing to "Tramadol").This information is not intended to be used as veterinary advice, nor to replace consultation with a qualified veterinarian.
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If you use the tramadol extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.
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6:31 PM, Anonymous said... We are seeing noticable improvments today. Our dog is still tender and will even squeal pretty good when he wakes up from a nap, or gets up too fast - but his behavior is markedly different. He seems so much more like his usual self. He had been going into a bathroom on the ground floor and sleeping most of the day. Tonight he came out and wanted to be on the couch with us again while we watched TV.We go to one prednisone per day now, and I have been easing back on the tramadol with only 4mg (instead of 5mg) per dose now. I'll try to ease that down as we get near the 14 days so that we run less of a risk of withdrawal symptoms. I'll update again in a few days or if anything changes.
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A human product called Ultracet® is available. It contains acetaminophen in addition to tramadol. This product is NOT safe for cats at any dose and requires specific veterinary instruction if it is to be used in dogs. Never use your own medication on your pet. Tramadol can cause seizures in humans and thus should be used cautiously in animals with a history of seizures.
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Take tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Do not take more than 300 milligrams of tramadol in one day.
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7:43 PM, me said... Tramadol does have addiction potential that specialists are finding of enough concern for humans that they provide other opiate type drugs while steering clear of tramadol. Animals cant obtain their own supplys to feed a psychological addiction. Psychological addiction is the only definition of the word addiction. Physical dependence is normal and needs to be considered with many drugs including anti depressants. Saying tramadol isnt addictive is untrue and simplifies what addiction is, which leads to greater misunderstanding and fear of using beneficial drugs. When tramadol, paxil and many other drugs came out they were touted as non addictive and with the least side effects. We know now that was a marketing lie. Paxil's withdrawl syndrome now has black box warnings for children and teenagers for risk of suicide while taking that medication. If tramadol works well for animals, wonderful, but it is a newer drug then most reliable opiates and experience has shown in humans that it isnt a safer drug addiction wise to opiates.
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anon said... My 5 year old basset hound hurt his back somehow a few days ago so we took him to the vets. He was walking fine although painful getting up. He was given dilaudid immediately at the ER which made him very incoordinated in his hind legs. SHe commented that he was a real light weight with the drugs.We left with metacam, tramadol and robaxin. All of these have a side effect of incoordination. It has not got any better and it going on 4 days now. His pain is better but the clumsiness persists. I called the vet and i reduced the doses. To check whether it is the meds or neuroloigical damage I stopped all meds yesterday.(Side note, still has reflexes, sensation and strength, bowel & bladder function). When should I expect to see the drug effects wear off. His last dose yesterday was 50mg of Tramadol 5pm, Robaxin 250mg 7am, and metacam 7am.
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If you have any questions about Tramadol , please talk with your doctor, pharmacist, or other health care provider. Tramadol is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. This information is a summary only. It does not contain all information about Tramadol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
... Comment #76: ic tramadol hcl acetaminophen par ...Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal. Overdose symptoms of a tramadol overdose may include drowsiness, shallow breathing, slow heartbeat, extreme weakness, cold or clammy skin, feeling light-headed, fainting, or coma. Tramadol may be habit-forming and should be used only by the person it was prescribed for. Tramadol should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death. Before taking tramadol
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Metabolism: Tramadol is extensively metabolized after oral administration. Approximately 30% of the dose is excreted in the urine as unchanged drug, whereas 60% of the dose is excreted as metabolites. The remainder is excreted either as unidentified or an unextractable metabolites. The major metabolic pathways appear to be N- and O-demethylation and glucuronidation or sulfation in the liver. Only the one metabolite (mono-O-desmethyltramadol denoted M1) is pharmacologically active. Production of M1 is dependent on the CYP2D6 isoenzyme of cytochrome P-450.
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