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11:29 AM, Anonymous said... Does Tramadol affect the kidneys at all? I have an old Rotti at 15 yrs .. She is very well aside from arthritis stiffness but had her spleen removed and has a bit of kidney issue with incontinence.. I wonder if this is an option for her any suggestions?JEnny
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Special Populations: Renal: Impaired renal function results in a decreased rate and extent of excretion of tramadol and its active metabolite M1. In patients with creatinine clearances of less than 30/ml/min adjustment of the dosing regimen is recommended (see DOSAGE AND ADMINISTRATION). The total amount of tramadol and M1 removed during a dialysis period is less than 7% of the administrator dose.
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2:13 PM, Anonymous said... My dog was biten by a copperhead a few hours ago. I could not aford the pain medication the Dr. offered(what college student could) but I did get the antbiotics. I have been prescribed Tramadol can I give him one or will it react with the venom. The vet said something about having to give an opiate based pain med so it would not react with the venom. Isn't tramadol a synthetic opiate?
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PRECAUTIONS: Tell your doctor your medical history, especially of: kidney disease, liver disease, seizure disorder, lung disease, history of drug or alcohol dependency, any allergies you may have. Limit alcohol as it may add to the dizziness or drowsiness effects caused by the medication. Because this drug may make you dizzy/drowsy, use caution performing tasks requiring alertness such as driving. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Tramadol is excreted into breast milk. Because the effects on a nursing infant are not known, consult your doctor before breast- feeding.
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Oral acetaminophen plus IV Propacetamol and oral plus IV Tramadol were also compared for pain management after tonsillectomy by Pendiville et al. They had treated patients with either 30 mg/kg of Propacetamol or 3 mg/kg of Tramadol before induction of anesthesia and acetaminophen suppository (15 mg/kg) or Tramadol drops (2.5 mg/kg) afterwards and at home. Although side effects of nausea and vomiting were comparable between the two groups, pain relief was considerably higher and need for rescue medication (IV diclofenac in the first 5 hours and oral Ibuprofen thereafter) was less in the Tramadol group (13).
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Tramadol is used to relieve pain, including pain after surgery. The long-acting tablets are used for chronic ongoing pain. . The effects of tramadol are similar to those of narcotic analgesics. Although tramadol is not classified as a narcotic, it may become habit-forming, causing mental or physical dependence.
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Oral acetaminophen plus IV Propacetamol and oral plus IV Tramadol were also compared for pain management after tonsillectomy by Pendiville et al. They had treated patients with either 30 mg/kg of Propacetamol or 3 mg/kg of Tramadol before induction of anesthesia and acetaminophen suppository (15 mg/kg) or Tramadol drops (2.5 mg/kg) afterwards and at home. Although side effects of nausea and vomiting were comparable between the two groups, pain relief was considerably higher and need for rescue medication (IV diclofenac in the first 5 hours and oral Ibuprofen thereafter) was less in the Tramadol group (13).
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4:42 AM, Anonymous said... First, thanks for the great info on this site. Our 14-year old lab/shep mix (75lbs) has severe arthritis in all four joints (dysplasia in hips, arthritis and swelling in front). He's very stoic, and doesn't whimper or cry, but in the last year, he's starting having a much more pronounced limp, and atrophy in the back, crossing of legs which indicates neurological problems, etc. At night (and often daytime too) he'd get very wrestless, panting, walking, panting, walking, looking to us for help, then panting and walking some more and he couldn't seem to calm down. (We tried Anapryl for adult cognative issues but it didn't help). His problem, of course, was that he was in pain, and the pain made him upset and anxious because he needed help. To treat that, the doctor prescribed Acepromazine as a sedative / anti-anxiety med and Tramadol for pain. For all of you out there with dogs who pant and pace and pant and pace, then lie down for three seconds and get right back up to pant and pace talk to your vet about Acepromazine. It reeeeeally helps calm them down so they can rest and let the pain meds do what they're supposed to do. Pain meds alone didn't do it for him, but the combination of Tramadol and Acepromazine has worked miracles.Acepromazine can be very sedating, so it takes some trial and error to find the right dosing. You want them comfortable but not comatose. He's sort of sleepy a lot, but he is 14, so he'd sleep a lot anyway. He gets up when we come in the door, and gets excited when the doorbell rings, he'll switch rooms and lie down near my husband or I depending on his mood, and take a nap there for a while. So he still enjoys life. He eats well, and even went to the dog park a couple of weeks ago for 15 minutes or so and had a great time smelling all the smells. This would not have been possible without the combination of these two meds.His regimin is: - 75mg Rimadyl 2xday; - 75mg Tramadol 2xday1 Lasix in morning (heart congestion which is controlled with Lasix)- 1/2 tablet Acepromazine breakfast, one whole tablet at dinner.- glucosamine/chondroitin 2xday - Fish oil 1xday (to help lubricate joints, help digestion, and build antioxidants)-Vitamin E 1xday (because fish oil can deplete Vitamin E)*****Also, for anyone who has trouble giving pills to your dog, try sticking the pills down into a small piece of hot dog. They'll eat it right up. With all the pills my guy gets, this has been a godsend!!Anyway, maybe this info will be helpful. I was at my wits end with the pacing and panting. he seemed desperate and I couldn't help him. Now it's very rare we have a night of pacing problems, annd as soon as we see it coming on, we give him a bit of extra meds and it calms him right back down and eases the pain so he can enjoy his night. For us, it's all about keeping him comfortable and happy as long as he's with us, and this has made a huge difference the last year. Good luck to others!Good luck.
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7:28 PM, Anonymous said... Great page. I have a 12 year old pomeranian that weighs about 5.5 lbs. He recently had several large teeth removed. He was prescribed tramadol orally after the surgery to control the pain. It was mixed into an oral suspension (I supposed because of the small size of the dog, in order to get the dosage right) and I was supposed to give .25 ml of a 100mg/5ml solution twice a day. So if I am doing my math right, that is 5mg per dose, 10mg per day.My dog has responded well to the surgery and was up and around very quickly and we are seeing no signs of infection or problems with the teeth. There was some scratching on his face as the stitches dissolved but never to the point of causing any problem and he seems to have cut way back on the scratching now.I took him off the tramadol within a couple of days because he seemed fine. However, we have noticed signs of mild constipation during the first week.This week it has gotten worse. He squeals in pain when you pick him up and he has gone two days without a bowel movement. He is eating lightly, but perhaps a little less than normal. He hasn't quit eating entirely though and still seems to enjoy Pupperoni Treats (What do they put in those things, cocaine? He goes nuts for them) if we break them into pieces.The squealing and screeching is extremely unnerving. He is so scared of being picked up that he squeals when you even act like you might be about to pick him up. It is heartbreaking, but also very frustrating because I don't know how much is pain, and how much is fear.I took the dog to the vet today and as you might expect, he did almost none of what I described above while we were at the office. The vet was able to get one light squeak out of him and that was it. The vet suggested doubling the dose of tramadol to manage the pain and tapering it off over the weekend to see if that helped.I mentioned the decreased number of bowel movements to our doctor, but at the time of the visit, it was a day and a half without a movement which is abnormal (he usually has one a day) but not extreme.Now it is 10pm and we are at two straight days and we spent a good deal of time outside walking him and trying to coax him into having a bowel movement to no avail.This leads me to believe that his problems may be gastrointestinal in nature and when we pick him up we are pressing on his belly and hurting him. It also leads me to my long-winded question: Should I continue the tramadol since it seems to have a slight incidence of constipation and it doesn't seem to be helping the pain.Also, off topic for this thread, but what is my best step on the constipation?Thanks for any help,-TS
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Tramadol is not passed to nursing young and should be an acceptable pain reliever for a lactating mother.
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SIDE EFFECTS: Tramadol may cause dizziness, weakness, incoordination, nausea or vomiting, stomach upset, constipation, headache, drowsiness, anxiety, irritability, dry mouth, or increased sweating. If any of these effects persist or worsen, inform your doctor. Notify your doctor if you develop any of these serious effects while taking this medication: chest pain, rapid heart rate, skin rash or itching, mental confusion, disorientation, seizures, tingling of the hands or feet, trouble breathing. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, breathing trouble. If you notice other effects not listed above, contact your doctor or pharmacist.
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