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2:22 PM, Anonymous said... My 15-year old border collie/Rott mix was just prescribed 1/2 pill of Tramadol twice a day. He is also on one Anipryl (l-deprenyl) each morning, and a 1/2 Deramaxx pill with evening dinner. (He limps and has trouble with stairs. Vet says he has nerve degeneration of the lower spine called something like, "spando..??). She also thinks he has arthritis and his back left hip may have been dislocated at some point because it twists a little when he walks. Is Tramadol and Anipryl safe together???? You say it's contraindicated.thankskaren
Tramadol is a novel analgesic having both opiate agonist activity and monoamine reuptake inhibition that contribute to its analgesic efficacy. Opioid activity is due to both the parent compound and the more active O-desmethylated metabolite. Tramadol acts on the monoamine reuptake systems by inhibiting the reuptake into nerve terminals of both norepinephrine and serotonin. Apart from analgesia, tramadol may produce a number of symptoms including dizziness, somnolence, nausea, and constipation similar to other opioids. High doses of tramadol, often in combination monoamine oxidase (MAO) inhibitors or serotonin-selective reuptake inhibitors (SSRIs), have been associated with a serotonin syndrome consisting of convulsions, hyperthermia, muscle rigidity and pain.
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What will you find here? Answers to pet owner questions about veterinary procedures, terminology, pharmaceuticals, nutraceuticals and other products; a place for techs to give voice to their frustration with vets who don't respect our skills, pet owners who don't take care of their pets, and co-workers who treat us with less than professional respect; in-depth looks at veterinary health issues; and our own patented Vet Tech Rants.
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... Comment #155: tramadol good pain reliever ...bone marrow micronucleus tests in mice and Chinese hamsters. Weakly mutagenic results occurred in the presence of metabolic activation in the mouse lymphoma assay and micronucleus test in rats. Overall, the weight of evidence from these tests indicates that tramadol does not pose a genotoxic risk to humans.
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Tramadol may cause drowsiness and dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Tramadol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tramadol ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness. Tramadol may cause dizziness; alcohol, hot weather, exercise, or fever may increase this effect. To prevent it, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of this effect. Tell your doctor or dentist that you take Tramadol before you receive any medical or dental care, emergency care, or surgery. Use Tramadol with caution in the ELDERLY; they may be more sensitive to its effects. Tramadol should not be used in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed. PREGNANCY and BREAST-FEEDING: Tramadol has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tramadol while you are pregnant. Tramadol is found in breast milk. Do not breast-feed while taking Tramadol . When used for long periods of time or at high doses, Tramadol may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Tramadol stops working well. Do not take more than prescribed.
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Less common or rareAbdominal fullnessAbnormal or decreased touch sensationBlisters under the skinBloatingBlood in urineBlood pressure increasedBlurred visionChange in walking and balanceChest pain or discomfortChillsConvulsions (seizures)Darkened urineDifficult urinationDizziness or lightheadedness when getting up from a lying or sitting positionFaintingFast heartbeatFrequent urge to urinateGaseous abdominal painHeart rate increasedIndigestionIrregular heartbeatLoss of memoryNumbness and tingling of face, fingers, or toesNumbness, tingling, pain, or weakness in hands or feetPain in arms, legs, or lower back, especially pain in calves and/or heels upon exertionPain or discomfort in arms, jaw, back or neckPains in stomach, side, or abdomen, possibly radiating to the backPale bluish-colored or cold hands or feetRecurrent feverSeeing, hearing, or feeling things that are not thereSevere crampingSevere nauseaSevere redness, swelling, and itching of the skinShortness of breathSweatsTrembling and shaking of hands or feetTrouble performing routine tasksWeak or absent pulses in legsYellow eyes or skinSome side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
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Follow the directions for using Tramadol provided by your doctor. Store Tramadol at room temperature, away from heat and light.
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7:12 PM, Anonymous said... My 2 year old chocolate lab was diagnosed with osteosarcoma yesterday. She has presented with a limp since mid-october but xrays have showed nothing until yesterday when finally they found evidence in her rear leg. Despite not weight bearing on that leg she has not whined, had trouble moving around etc. and has been very happy and well adjusted. After yesterdays xrays when she was coming out of sedation she was whimpering and it didn't taper off so the doctor prescribed 50mg of tramadol three times a day. She is about 70 lbs. When I came home from work today she managed to limp down the stairs to greet me. I gave her the afternoon dosage and shortly afterwards she began whining, really whining. She has not moved, will not elmininate (#1 or #2) even when I carry her outside. She is unable to do even the three stairs at all. She was FINE when I brought her in yesterday in all of these regards and although I know bone cancer is extremely painful I am having trouble believing that overnight she went from painfree (unless joint was palpated) to unable to walk at all and miserable). I am more concerned that she might be experiencing side effects of the tramadol. She is also disoriented and when she has tried to move has walked into doors etc. Should I decrease the dosage or discontinue? I don't want her to be in pain but what if the tramadol is making it worse instead of better???????
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5:12 PM, Anonymous said... Hi! Does anybody know if Tramadol and DGP (Dog Gone Pain Supplement)be taken together, or Tramadol and Vetrin (buffered Aspirin for dogs)Safe taken together?? My dog is suffering with alot of left shoulder pain might be caused by bone cancer or OCD and Joint pain. She is a 92 pound Rottie. 9 years old. They had her on Previcox (New NSAID)but when given to her for awhile she would be very incoordinated, weak in back legs and pant heavy. I want to take her off this med. and try the DPG and Tramadol or Aspirin and Tramadol. ThanksKW.
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The potential market for a once-daily tramadol treatment, however, is considerably larger. Compliance with multiple-times daily dosing regimens can be challenging for patients, potentially limiting the efficacy of a drug. A once-daily formulation of tramadol offers significant value and satisfaction to both patients and physicians through the potential to improve compliance.
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... Comment #223: tramadol hcl 50 mg how much to give my dog ...6:59 AM, Anonymous said... I have a 4 YO Irish Setter who was on Previcox for 6 months that caused a perferation in his digestive track that almost killed him. ONly the skills hands of a outstanding surgeon saved him. The surgeon placed him on Tremadol, 3 tabs twice daily. Now another vet says thats too much and that he should not be put on Tremadol for the long term. Ruben has spondylosis that is symptomatic. Can Tremadol be used long term? If not what else would you recommend? Thanks
Side effects from treatment with tramadol may be decreased by a slow increase in dose, as directed by your doctor. The tablets can easily be broken in half at the score if needed. The maximum dose of tramadol for an average healthy adult is 100 mg per dose, every 4 to 6 hours, up to 400 mg per day. People over 75 years of age should not take more than 300 mg per day. People with liver or kidney disease may need lower daily doses. Follow your doctor's directions.
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The analgesic effects of tramadol are not completely reversed by the opioid antagonist naloxone and some patients who do not respond to codeine do respond to tramadol. This suggests that tramadol has additional mechanisms of action. Tramadol inhibits reuptake of serotonin and noradrenaline and this probably contributes to its analgesic effects.
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Design Patterns refer to generics as 'parameterized types', which are also known as 'generics' (Ada, Eiffel, Java, C#, VB .NET) or 'templates' (C++). These allow a type to be defined without specifying all the other types it usesthe unspecified types are supplied as parameters at the point of use. The authors note that this technique (especially when combined with delegation) is very powerful, and also that: "Dynamic, highly parameterized software is harder to understand than more static software." (
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Do not drink alcohol while you are taking tramadol. Alcohol may cause a dangerous decrease in your breathing when used together with tramadol. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tramadol. Tell your doctor if you regularly use any of these other medicines. Tramadol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Tramadol side effects
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4:42 AM, Anonymous said... First, thanks for the great info on this site. Our 14-year old lab/shep mix (75lbs) has severe arthritis in all four joints (dysplasia in hips, arthritis and swelling in front). He's very stoic, and doesn't whimper or cry, but in the last year, he's starting having a much more pronounced limp, and atrophy in the back, crossing of legs which indicates neurological problems, etc. At night (and often daytime too) he'd get very wrestless, panting, walking, panting, walking, looking to us for help, then panting and walking some more and he couldn't seem to calm down. (We tried Anapryl for adult cognative issues but it didn't help). His problem, of course, was that he was in pain, and the pain made him upset and anxious because he needed help. To treat that, the doctor prescribed Acepromazine as a sedative / anti-anxiety med and Tramadol for pain. For all of you out there with dogs who pant and pace and pant and pace, then lie down for three seconds and get right back up to pant and pace talk to your vet about Acepromazine. It reeeeeally helps calm them down so they can rest and let the pain meds do what they're supposed to do. Pain meds alone didn't do it for him, but the combination of Tramadol and Acepromazine has worked miracles.Acepromazine can be very sedating, so it takes some trial and error to find the right dosing. You want them comfortable but not comatose. He's sort of sleepy a lot, but he is 14, so he'd sleep a lot anyway. He gets up when we come in the door, and gets excited when the doorbell rings, he'll switch rooms and lie down near my husband or I depending on his mood, and take a nap there for a while. So he still enjoys life. He eats well, and even went to the dog park a couple of weeks ago for 15 minutes or so and had a great time smelling all the smells. This would not have been possible without the combination of these two meds.His regimin is: - 75mg Rimadyl 2xday; - 75mg Tramadol 2xday1 Lasix in morning (heart congestion which is controlled with Lasix)- 1/2 tablet Acepromazine breakfast, one whole tablet at dinner.- glucosamine/chondroitin 2xday - Fish oil 1xday (to help lubricate joints, help digestion, and build antioxidants)-Vitamin E 1xday (because fish oil can deplete Vitamin E)*****Also, for anyone who has trouble giving pills to your dog, try sticking the pills down into a small piece of hot dog. They'll eat it right up. With all the pills my guy gets, this has been a godsend!!Anyway, maybe this info will be helpful. I was at my wits end with the pacing and panting. he seemed desperate and I couldn't help him. Now it's very rare we have a night of pacing problems, annd as soon as we see it coming on, we give him a bit of extra meds and it calms him right back down and eases the pain so he can enjoy his night. For us, it's all about keeping him comfortable and happy as long as he's with us, and this has made a huge difference the last year. Good luck to others!Good luck.
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Tramadol can be used for pain relief in both dogs and cats. (Most non-steroidal anti-inflammatory drugs are not safe for feline use so tramadol provides a nice choice for cats with chronic pain issues).
Are brand-name and generic warfarin interchangeable? Multiple n-of-1 randomized, crossover trials.". Ann Pharmacother 39 (7-8): 1188-93.
... Comment #84: tramadol app ...Nancy Campbell RVT said... Sorry I didn't respond sooner. I've had a full plate the past few weeks. I'm glad you took your dog to another vet. It sounds like you had far better communication with the new one and you were able to help your dog better. Good luck and good healing.
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Qureshi N.A., al-Ghamdy Y.S., al-Habeeb T.A. (2000). "Drug addiction: a general review of new concepts and future challenges".
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If you have any questions about Tramadol , please talk with your doctor, pharmacist, or other health care provider. Tramadol is to be used only by the patient for whom it is prescribed. Do not share it with other people. If your symptoms do not improve or if they become worse, check with your doctor. This information is a summary only. It does not contain all information about Tramadol . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
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2:13 PM, Anonymous said... My dog was biten by a copperhead a few hours ago. I could not aford the pain medication the Dr. offered(what college student could) but I did get the antbiotics. I have been prescribed Tramadol can I give him one or will it react with the venom. The vet said something about having to give an opiate based pain med so it would not react with the venom. Isn't tramadol a synthetic opiate?
MedicineNet®Copyright © 2007 by RxList Inc.RxList does not provide medical advice, diagnosis or treatment.
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A good pain reliever for moderate to severe pain is the analgesic medication Tramadol. Also called Ultram, this pain reliever is not a member of the NSAID (nonsteroidal anti-inflammatory drug) class of medications that are commonly prescribed for pain. It is not a narcotic drug either. Tramadol is a unique medication that has properties of both NSAIDs and narcotics while not having the negative side effects of either one.
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