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  Methadone for tramadol addicts? Generic drug companies may also receive the benefit of the previous marketing efforts of the brand-name drug company, including media advertising, presentations by drug representatives, and distribution of free samples. Many of the drugs introduced by generic manufacturers have already been on the market for a decade or more, and may already be well-known to patients and providers (although often under their branded name). Info Only - Ad Free! Competing interests: Professor Schug has been and is involved in clinical research on tramadol, partially funded or supported by Grünenthal GmbH, Stolberg, Germany and CSL (New Zealand) Ltd., Auckland. If you have a question about a drug that you are taking or Christie Keith said... Obviously we can't know for sure what is going on with your dog. In general, I'd say that it IS hard to know if this is an opioid response (Tramadol is sort of an opioid and sort of not)or if it's from pain. Usually, this kind of opioid response is accompanied by whining and a lack of recognition of the owner. In fact, whining is the single symptom the first vet who prescribed Tramadol to a dog of mine warned me about, as being from too high a dose for that dog. I have never seen it from Tramadol, but I have seen it from Fentanyl and from morphine. This does not sound like what your dog is experiencing, however.Sometimes we do see dogs whose owners say they are "sedated" when what they are is finally getting some deep sleep because their pain is under control. This does not at all sound like what you are describing, either.So, the answer is ... you need to talk to a vet who IS familiar with Tramadol and with pain management. This will be easy. Your vet can simply call and do a consult with any vet school's anesthesia consultants. They will be able to tell him how to evaluate the effect of this drug on your dog.Your vet also could go onto VIN (if he or she is not already a member, they can obtain a free 30 day trial membership; www.vin) and consult with the analgesia/anesthesia consultants there. It sounds to me like your dog is in a lot of pain and really needs some expert pain management here. Fortunately, that IS available, even if your own vet isn't an expert in that area. Please let us know how he does!Christie and Nancy
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