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4:12 AM, Anonymous said... I just wanted to comment that although Tramadol is non-narcotic, it still can be addicting in humans. Long term use in animals have not yet been established but if the animal is on Tramadol for an extended period of time, weaning may be necessary to avoid withdrawls, such as with long term use with narcotics. Withdrawls in humans have been documented to be comparable to withdrawl from narcotics such as morphine. These withdrawls have been noted to last from 3 to 5 days in the moderate to severe stages with lingering effects for up to 14 days.Dr.Helena S., DVMCharlotte, NC
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Consult your pharmacist or physician if you have questions about drug interactions with Tramadol.
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El tramadol debe administrarse con especial precaución en caso de padecer alguna de las siguientes enfermedades: adenoma de próstata, estrechamiento de la uretra, asma, enfermedad pulmonar obstructiva crónica, hipotiroidismo, enfermedad inflamatoria intestinal grave, presión intracraneal elevada, lesión cerebral o enfermedades del hígado o del riñón.
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8:08 AM, Anonymous said... Is tramadol a good fit for bursitis? I have an almos 11 year-old greyhound, approx. 80#. He has chronic bursitis in his shoulder. It seems to give him quite a bit of pain, either limping profoundly and/or refusing to put weight on the leg while standing. He also pants a lot, especially in the evening. He is currently taking deramaxx but he still pants and my sense is that the deramaxx is relieving the pain some, but not completely. The bursitis seems to get better for a while, and about the time he seems pretty normal in his movements, starts the heavy limping and panting again. I'm wondering if adding tramadol to the deramaxx would be a good protocol for this condition. Are there any other treatments for this condition that I could pursue. What do you think about homeopathic remedies, ointments, etc.?
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Nancy Campbell RVT said... Tramadol is very bitter and unpleasant. Drooling is something dogs (and cats) will do if they get a taste it.
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Tramadol is called Ultram in the U.S, it appears on the site under that name, but I've never heard it called that in England. I've been taking Tramadol for three years, and although it helped with the pain initially the side effects are dramatic. It now no longer helps the pain, but my body is completely addicted, so I'm attempting to come off them slowly. They make me tired a lot of the time, faint, nauseous, very dehydrated, I have to sleep for much longer periods, sleep is unpleasant and interrupted, and I get viruses very easily. I think it could be advisable to take Tramadol in very acute periods of RSD, but not long term. Lucy - Oxford, England I have been taking Pregabelin (Lyrica) for a number of weeks now, along with Tramadol. I am very aware that when I take a full dose of both drugs together I feel a very strange almost "spaced out" feeling. I feel unsteady on my feet and find it difficult to walk a few yards without having to hold on to something to steady myself. If I reduce the Pregabelin dose it is a bit better. I would be interested to hear from anyone with similar experiences when using both drugs. Andy - Taunton, Somerset, UK
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4:02 PM, Anonymous said... My yorkie is 4 1/2 years old. He had neuro surgery last June for COMS/syringomyelia. This is an awful disease. He has been on pred now for over a year, I cannot wean him off due to pain. He is also on liquid neurontin 3 times a day. My local vet spoke with the neurologist a few months ago when none of the above was controlling Noahs pain. They added Tramadol. It is a 50 mg tab and I was told to give 1/4 prn for pain. Lately we have had more bad nights than good. I have had to give 1/2 tab instead of 1/4 for 2 days now. Today he had BM which had fresh blood also. I am trying not to freak as otherwise he appears okay. I jsut found this website and saw nothing about GI Bleed. So any history of such? Does Tramadol come in another dosing size that would be easier to measure. Noah use to be 4 pounds, now with all the pred he is at 9. I know this is weight is too much but I can't get him off it with the steriods. I also wonder if he may have developed Hemorrhoids due to the weight/pressure when squatting to poop? Any thoughts?FYI the tramadol has been our saving grace many nights when he is hurting so bad, it kicks in within 20-30 minutes and he finally wll have peace.AD Alabama
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Tramadol may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, drowsiness, or decreased breathing may occur if tramadol is taken with any of these medications. Tell your doctor about all medicines that you are taking, and do not take any other prescription or over-the-counter medicines, including herbal products, without first talking to your doctor during treatment with tramadol.
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7:35 PM, Anonymous said... Christie Keith, you said that Tramadol can be a problem for cats, causing odd problems. Can you elaborate?Mark - CA
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Nancy Campbell RVT said... Tramadol is very bitter and unpleasant. Drooling is something dogs (and cats) will do if they get a taste it.
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Plasma concentrations of racemic tramadol are predictable over a 50 mg to 100 mg single-dose range. This is also true under multiple-dose conditions. Steady state is achieved after two days of dosing Ultram by a 100 mg q.i.d. regimen (maximum plasma concentration was 592 ± 177 ng/ml). The plasma half-life of tramadol following a single and multiple dosing was 6 and 7 hours, respectively. This increase in half-life upon multiple dosing is not considered to be clinically significant or to warrant dosage adjustment for chronic use.
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7:28 PM, Anonymous said... Great page. I have a 12 year old pomeranian that weighs about 5.5 lbs. He recently had several large teeth removed. He was prescribed tramadol orally after the surgery to control the pain. It was mixed into an oral suspension (I supposed because of the small size of the dog, in order to get the dosage right) and I was supposed to give .25 ml of a 100mg/5ml solution twice a day. So if I am doing my math right, that is 5mg per dose, 10mg per day.My dog has responded well to the surgery and was up and around very quickly and we are seeing no signs of infection or problems with the teeth. There was some scratching on his face as the stitches dissolved but never to the point of causing any problem and he seems to have cut way back on the scratching now.I took him off the tramadol within a couple of days because he seemed fine. However, we have noticed signs of mild constipation during the first week.This week it has gotten worse. He squeals in pain when you pick him up and he has gone two days without a bowel movement. He is eating lightly, but perhaps a little less than normal. He hasn't quit eating entirely though and still seems to enjoy Pupperoni Treats (What do they put in those things, cocaine? He goes nuts for them) if we break them into pieces.The squealing and screeching is extremely unnerving. He is so scared of being picked up that he squeals when you even act like you might be about to pick him up. It is heartbreaking, but also very frustrating because I don't know how much is pain, and how much is fear.I took the dog to the vet today and as you might expect, he did almost none of what I described above while we were at the office. The vet was able to get one light squeak out of him and that was it. The vet suggested doubling the dose of tramadol to manage the pain and tapering it off over the weekend to see if that helped.I mentioned the decreased number of bowel movements to our doctor, but at the time of the visit, it was a day and a half without a movement which is abnormal (he usually has one a day) but not extreme.Now it is 10pm and we are at two straight days and we spent a good deal of time outside walking him and trying to coax him into having a bowel movement to no avail.This leads me to believe that his problems may be gastrointestinal in nature and when we pick him up we are pressing on his belly and hurting him. It also leads me to my long-winded question: Should I continue the tramadol since it seems to have a slight incidence of constipation and it doesn't seem to be helping the pain.Also, off topic for this thread, but what is my best step on the constipation?Thanks for any help,-TS
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5:12 PM, Anonymous said... Hi! Does anybody know if Tramadol and DGP (Dog Gone Pain Supplement)be taken together, or Tramadol and Vetrin (buffered Aspirin for dogs)Safe taken together?? My dog is suffering with alot of left shoulder pain might be caused by bone cancer or OCD and Joint pain. She is a 92 pound Rottie. 9 years old. They had her on Previcox (New NSAID)but when given to her for awhile she would be very incoordinated, weak in back legs and pant heavy. I want to take her off this med. and try the DPG and Tramadol or Aspirin and Tramadol. ThanksKW.
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anon said... My 5 year old basset hound hurt his back somehow a few days ago so we took him to the vets. He was walking fine although painful getting up. He was given dilaudid immediately at the ER which made him very incoordinated in his hind legs. SHe commented that he was a real light weight with the drugs.We left with metacam, tramadol and robaxin. All of these have a side effect of incoordination. It has not got any better and it going on 4 days now. His pain is better but the clumsiness persists. I called the vet and i reduced the doses. To check whether it is the meds or neuroloigical damage I stopped all meds yesterday.(Side note, still has reflexes, sensation and strength, bowel & bladder function). When should I expect to see the drug effects wear off. His last dose yesterday was 50mg of Tramadol 5pm, Robaxin 250mg 7am, and metacam 7am.
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Many people are concerned about the side effects of narcotic medications, such as the opiates Vicodin, Oxycontin, Morphine and Demerol. These medications have all been in the news because of their serious negative effects. Also, unlike NSAIDs, Tramadol drug does not cause stomach upset or irritation. It is not surprising, then, that Tramadol is the pain reliever that many physicians prefer to prescribe. It can be used to treat many types of pain and pain syndromes. It is often prescribed after surgery or for people with chronic pain conditions like arthritis and fibromyalgia.
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Tramadol (Tramal™) is a synthetic, centrally acting analgesic used parenterally and orally for the treatment of moderate to severe pain. It was approved in New Zealand in 1997, but it is not currently funded. Its potency is comparable to that of pethidine, but in severe pain morphine is possibly superior.
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The Cult of Pharmacology: How America Became the Most Troubled Drug Culture by Richard DeGrandpre, Duke University Press, 2006. Nestler, Eric and Malenka, Robert (March 2004). "The Addicted Brain". Scientific American, pg. 78-83. Leavitt, Fred (2003) The REAL Drug Abusers. Rowman & Littlefield.
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9:02 AM, Anonymous said... Thanks for the responses. We started our dog on a tramadol/methocarbamol/prednisone regimen Friday (yesterday) around 5pm. By 10pm we could see a noticable improvement, but definitely not a magic cure. (I didn't expect one, but I was pleased to see us at least partially managing the pain.)He slept through most of the night, with an occasional whimper. I think these occur when he wakes and shift positions and catches something wrong. (He sleeps at the foot of our bed, he is a 5.6 lb pomeranian.) We had one squealing/screeching incident and it was my fault, I had gotten up and thought he was awake, and went to pet him. It startled him and he was probably squealing out of fear/pain from the sudden start. I won't make that mistake again!I took him out this morning. His tail is occasionally at full mast, but sometimes he has it at about half mast. Two days ago it was tucked completely between his legs and he was walking with his back down low. This is an improvement for sure, but of course I want my old dog back ASAP! My vet said to expect significant results by Monday.Just to clear things up about the different vets, we had an ongoing problem with the dog's teeth and finally decided it was worth the risk of anesthesia at his age to get them pulled. Our "regular" vet did not handle procedures this in-depth. So we went to another for this. I had taken my dog back to the "other vet" when we saw these symptoms thinking it might be related, but after that vet seemed to be at a loss (he just upped the dosage of the tramadol) and the dog continued to worsen, I wanted another look.My "regular vet" immediately performed a test where he rolled the dog's back feet forward as if he was standing on his "knuckles" and showed me how slow he was to correct the situation and move back to the pad of his foot. I was told this was a classic sign of this type of back problem.So we have him back down to his regular dose of tramadol (5mg twice a day) and we are using (if I am reading the labels correctly) 1.25 mgs twice a day with the prednisone for three days, then 1.25 mgs once a day for three days, then 1.25 mgs every other day until 14 days. Finally we have the methocarbamol at 40mg twice a day for 14 days.If those are way off, I might have misread the labelling. The tramadol is labelled differently than the others. The bottle says 100mg/5ml and we are giving .25 ml twice a day. So by my math that is 5mg a dose, twice a day. The other bottles are labelled per dose - the prednisone is 1.25mg/0.5ml which is the amount we are giving him each time and the methocarbamol is labelled 40mg/ml and we are giving him 1ml per dose, twice a day. Our local pharmacist went to a lot of trouble to make the suspensions and he told me that he tried to add some peanut butter flavor to make it more palatable. It smells good enough, and he doesn't fight me when I am giving it to him - so that is good.Sorry this is so long, but I love having things reviewed to make sure we are getting him the best care possible - and hopefully this will help someone else down the line. It is very reassuring to find a similar case when you are having a problem with your pet and you see that someone else has dealt with it (hopefully successfully) with the same, or similar treatment as you are getting. We are dealing with constipation (or refusal to go for fear of pain) again, but it is only two days and he waited about 2 1/2 days last round. He is eating normally and drinking a lot right now. Hopefully that is everything. Thanks so much for the responses.-TSGreenville, SC
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