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Nancy Campbell RVT said... How long had the pain patch been in place? It takes approximately 12 hours minimum before it reaches full affect. It's usually applied at least 24 hours in advance. If it's been on less than 24 then it's not yet reached full affect. Contact your veterinarian for advice since your dog cannot tolerate the NSAID Rimadyl. There are other options to help your dog get some relief. I hope all is better soon!
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Take Tramadol by mouth with or without food. If you miss a dose of Tramadol , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Tramadol .
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9:08 AM, Anonymous said... My senior dog has been on tramadol for a couple weeks now but it seems to make him woozy at times. He gets 25 mg in the morning and around 10 p.m. He hasn't slept well at night for the last year or so and the tramadol does seem to help with that sort of. At night, he usually sleeps for an hour or so then is up and pacing fairly quickly for an hour or so around midnight, which makes me think it helps the pain. Then he goes to sleep for a couple hours, but wakes up again around 4 a.m. Sometimes I get up with him and he walks around a little, and sometimes I can just lay him on his other sides and he goes back to sleep and sleeps very soundly the rest of the night. When I have to wake him up in the morning so I can go to work, he seems disoriented. He circles to the right constantly and can hardly walk in a straight line, even with me leading him by collar and tail. (He does this a little bit anyway, which may be a pain or injury thing, but he does it much more after tramadol.) My dog weights 43 lbs. I started chipping off a little piece of his Tramadol pill to give him a smaller dose to see if that helps. My vet just began prescribing tramadol and doesn't have any experience with it yet. Any suggestions? Does this sound like it's from the tramadol or could it just be a pain response?
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8:38 PM, Susan in Montana said... I have a question about Tramodoland Deramaxx, too, I guess. My vet had prescribed Deramaxx for our 10-year-old Golden Retriever's arthritis and I had been giving him the maximum dose since last summer. A few weeks ago I took him in to the vet. They did some blood tests and discovered elevated creatinin, indicating decreased kidney function. We did two more blood tests after that, finding that his creatinin was indeed elevated. The vet took him off the Deramaxx and put him on Tramadol. I am concerned because some websites say that Tramadol is not good if a dog has compromised kidney function. I am noticing also that he is now drinking more wateris this a good sign or a bad sign? Is the decreased kidney function from the use of Deramaxx permanent? Thanks so much for your help.
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Nancy Campbell RVT said... If I were in your shoes I would find a new 24/7 hospital pronto. There's no point in dealing with vets you don't trust. Even if you have to drive several hours, wouldn't it be worth the peace of mind?
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Harati Y, Gooch C, Swenson M, et al (2000). "Maintenance of the long-term effectiveness of tramadol in treatment of the pain of diabetic neuropathy". J. Diabetes Complicat. 14 (2): 65–70.
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Metabolism: Tramadol is extensively metabolized after oral administration. Approximately 30% of the dose is excreted in the urine as unchanged drug, whereas 60% of the dose is excreted as metabolites. The remainder is excreted either as unidentified or an unextractable metabolites. The major metabolic pathways appear to be N- and O-demethylation and glucuronidation or sulfation in the liver. Only the one metabolite (mono-O-desmethyltramadol denoted M1) is pharmacologically active. Production of M1 is dependent on the CYP2D6 isoenzyme of cytochrome P-450.
Take this medication with a full glass of water. Tramadol can be taken with or without food, but take it the same way each time.
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Nancy Campbell RVT said... How much does your Irish Setter weigh? I've not heard any reason why a dog wouldn't be able to remain on Tramadol, if it is helping with pain.
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