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  ...1:54 PM, Anonymous said... I am writing to ask for help on my almost 15 year old siberian husky, who has been pretty healthy until the last few months. She was attacked by another dog at the kennel, had her ear bitten up and has had multiple infections and fluid in it since, losing hearing and eye sight on the right side of face. She has had renal insufficiency since 2003, but done well with use of glucosamine and chondrotin for arthritis. She has had to be on NSAIDS (Rimadyl, then Deramaxx and Tramadol periodically) for pain and swelling related to this attack. About one month ago, after becoming dehydrated for refusing to eat because the kennel (first time staying at the owner's home since the attack), forgot to give her her Deramaxx making it painful to eat, her weight dropped, Hematocrit dropped from 40 to 35, and her kidney enzymes skyrocketed, with a BUN of 123, Creatinine of 5.23 and Phosphorus of over 7. Also, learned her thyroid had shot up to T-4=6.5; she had been diagnosed Hypothyroid in September after she developed a pacing/panting episode pattern during the night. She had improved on this with discontinuing Tramadol, moving from Rimadyl to Deramaxx and starting .8 of L-thyroxine, and I had been giving her two capsules each day of Calcium Lactate (a phosphurus binder). After her numbers were so high, she was prescribed Epakitin ( a prescription phosphorus binder) and her numbers all significantly dropped, bringing her BUN down to 69. Unfortunately, she fell on Thanksgiving weekend and hurt her tailbone, ending up the local emergency vets on fluids and drugged up with hydromorphine, causing her to fall over and over again hitting her tailbone. I got her out of there and drove to a veterinary medical school a few hours away. She was found to have a UTI and about 25% kidney function and no broken bones. She's on doxycycline for the UTI and also started on Enalapril for hi BP she developed after her fall. No One can check with an MRI for slipped disc because she can't tolerate general anesthesia because of the kidney failure. Her numbers were all high again. My vet and the med school are coordinating care for her since then. Her numbers came down last week after being back on Epakitin, being off all NSAIDS and off her L-thyroxine (she's back to Hypothyroid again). She's started pacing again and the vet recommmended Tramadol, and I finally convinced her to restart .4 L-thyroxine, but just read the comment by Anonymous 4:42 am, aboout Acepromazine (does this affect the kidneys?). My dog's kidney numbers went back up last week, which may be related to use of Tramadol again 50 mg b.i.d., eating human tuna fish without the Epakitin added, as my dog stopped eating her prescription food with all the meds added. Just found something she'll eat with the Epakitin in it, called Spot's Stew, low protein, natural canned food from the pet store, with some regular chicken pieces added to entice her. The pacing and panting continue and after reading this site, I'm going to try and give her the Tramadol in four 25 mg doses. Also, I'll call the vet on Monday to see what she thinks about the Acepromazine. The description of this dog that benefited sounds just like my Nikita, who will almost get laid down, and then pop back up to pace over and over again, during the night. We've had over a week of sleepless nights, so I'm desperate to here back thoughts of folks on this website. I can tell by reading you're all dog-lover's and educate yourself as much as you can on your pets. What I've learned is that it is not the protein in food causing problems with kidney function, but the phosphorus that clogs them up, so a good phosphorus binder is important to use to help your dog's kidneys. I started with the Calcium Lactate OTC Capsules, and now the Epakitin seems to help, but unsure how these other variables are affecting the enzyme tests. I will keep you and your pets in my prayers and ask you do the same for Nikita and me. I look forward to any ideas, feedback. Thanks. Sleepless in Bellevue! ...
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  ...Case Study 3 / 2:41 AM, Anonymous said... Hello,My 11 year old Doberman was recently prescribed Rimadyl for arthritic pain. Aside from very occasional temporary stiffness, her only symptom was trembling. She would do this trembling a few times a day, for several seconds or a minute. It is pretty much the same sort of trembling a dog would do if she is cold. Aside from that, she is very healthy and active, and you would never guess she is in pain. She chases balls, is 15 feet in front of me on walks, runs, jumps, smiles, etc. She will even wag her tail and lick me during the trembling episodes.Anyway, I got a weeks worth of Rimadyl because my vet is convinced the trembling is because of pain, and the trembling/shaking seemed to decrease somewhat, though she still had the shaking sometimes. When discussing the high cost of Rimadyl, my vet said I could try Tramadol instead, as it is cheaper. So right now she is on her last (7th) day of Rimadyl, and starts Tramadol tomorrow. With Rimadyl, she takes 75mg twice a day. Tramdol is prescribed at 50mg from 1-4 times a day PRN. My dog weighs approx 70 pounds.My questions are.. should the Rimadyl have completely stopped the trembling if the trembling is pain-associated? Also, why would a vet recommend Rimadyl before Tramadol if Tramadol is safer and cheaper?I don't doubt that my dog has some pain, but I am not yet convinced that the trembling is completely pain-related. She did have a complete workup before starting the Rimadyl and her kidneys, liver and everything is fine.I am just worried a bit about being the one to decide if she is in pain, and to decide what to does... especially since the Rimadyl didn't totally get rid of the trembling. I plan on starting her out on 1/2 pill twice a day and go from there. The Rimadyl seems "easier" as far as dosing, as the pet-pwner doesn't "decide" how much to give per day... but if it didn't stop, was it only partially working?I can't affiord to send my dog to a specialist to determine if she has some other condition that causes the trembling, like a neurological condition. The tests that my vet did all came back great.I just hate the idea of giving my dog medications if she really doesn't need them.Any suggestions or advice?Thanks so much! ...
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  ...order concentration; Abnormal digoxin (Lanoxin, Lanoxicaps); 12:41 PM, Anonymous said... I have a 3yr old llaspo apso mixed with a shitatsu who is vomiting and have loose stool, is there anything I can give her until I take her to vet on tuesday Lung Cond. imatoy said... Sorry, not sure when the last comment was made on this, but i'll try nonetheless.i have a 13 year old lab mix who has pretty bad arthritis and has been on thyroid medication and tramadol since April. she's like a brand new dog! however, i'm having slight issues with the vet and prescribing her more of the tramadol. they have said that i need to bring her in every 6 months for a re-evaluation of her thyroid medication, and have tacked on to that now a blood panel because of the tramadol.is this normal? or is my vet being either 1) overly cautious or 2) making me do blood tests that are unnecessary?I asked about why Tramadol would require constant blood tests(especially since this was a different vet in the office and the first one expressly said that Tramadol was a great pain medication because it didn't harm the GI tract)and was told that it too was an NSAD that could have liver problems.is this true?any help would be wonderful! ...
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  ...Pain Relief a history of drug or alcohol addiction; Visit the tramadol Index » News | Tramadol versus venlafaxine Urinary frequency; order The fact that I had a minor stroke before I was placed on tramadol could have exacerbated my symptoms. I found that it changed my moods and I became irritable and confused. My anxiety never went away. Although I was using it for pain it actually increased the pain slightly before it soothed it which is quite strange. However this is my own particular experience. Tramadol is used to treat post-operative and/or chronic (e.g. cancer-related) pain in dogs and cats. $178.60 Knee Cartilage Restoration Advances in technology are helping painful old knees work like new again. See more placenta. The mean ratio of Spiller H, Gorman S, Villalobos D, Benson B, Ruskosky D, Stancavage M, et al. Prospective multicenter evaluation of tramadol exposure. Clinical Toxicology 1997;35:361-364. patent has expired, 2) the generic company certifies the brand company's patents are either invalid, unenforceable or will not be infringed, 3) for drugs which have never held patents, or 4) in countries where a patent(s) is/are not in force. The expiration of a patent removes the monopoly of the patent holder on drug sales licensing. ...
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